Professor Giovanna Mallucci 

Giovanna Mallucci is a Principal Investigator at Altos Labs, Cambridge Institute of Science and Honorary Professor of Molecular Neuroscience at the University of Cambridge. She was previously Center Director of the UK Dementia Research Institute and Van Geest Professor of Clinical Neurosciences at the University of Cambridge. Her undergraduate degrees were in Physiological Sciences and Medicine from the University of Oxford and University College, London. She obtained her PhD from London University, for which she generated the first adult onset mouse model of prion protein knockout that paved the way to her discoveries about reversibility of early neurodegeneration. Her lab pioneered the understanding of the role of the Unfolded Protein Response (UPR) in neurodegenerative diseases and its therapeutic manipulation for neuroprotection, including discovering repurposable drugs now in clinical trials for dementia. Giovanna’s interest in neuroprotection led to the discovery of ‘hibernation’ proteins in synapse regeneration that can be targeted therapeutically. She is Fellow of the Academy of Medical Sciences (2017) and has received numerous national and international awards, including SciAm50 award for leadership in research as one of the top 50 scientific innovators worldwide and the 2021 Potamkin Prize for Research in Pick’s, Alzheimer’s and Related Disorders. Giovanna is a practicing neurologist, specialised in dementia.